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Drug Name | CAR2 anti-CD38 A2 CAR T cells |
Trade Name | |
Synonyms | PNK-CAR38|CAR2 Anti-CD38 A2 CAR-T Cells|CD38-A2 CAR2-expressing T-cells |
Drug Descriptions |
CAR2 anti-CD38 A2 CAR T cells comprise engineered natural killer cells derived from placental stem cells that contains a second generation chimeric antigen receptor (CAR) targeting CD38 linked to CD28 and CD3 zeta chain, which potentially enhances lysis of tumor cells expressing CD38, and reduces tumor burden (Blood (2019) 134 (Supplement_1): 2070). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C156170 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CAR2 anti-CD38 A2 CAR T cells | CAR2 anti-CD38 A2 CAR T cells | 0 | 1 |