huCART19
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| Drug Name | huCART19 |
| Trade Name | |
| Synonyms | huCTL019|CTL119|autologous anti-CD19 CAR-CD3zeta-4-1BB-expressing T cells |
| Drug Descriptions |
huCART19 comprise autologous T-cells engineered to express a humanized chimeric antigen receptor (CAR) that targets CD19, as well as CD3zeta chain and 4-1BB, which may result in increased T-cell response against CD19-expressing tumor cells (NCI Drug Dictionary, PMID: 38615142). |
| DrugClasses | CD19 Immune Cell Therapy 72 |
| CAS Registry Number | NA |
| NCIT ID | C156271 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CART22-65s cells + huCART19 | CART22-65s cells huCART19 | 0 | 2 |
| huCART19 | huCART19 | 0 | 5 |
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