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Drug Name | BMS-188667 |
Trade Name | |
Synonyms | Abatacept|BMS 188667|BMS188667|RG2077|RG1046|CTLA4-IGG4M|Orencia |
Drug Descriptions |
Abatacept (BMS-188667) is a recombinant protein containing the extracellular domain of CTLA-4 fused to immunoglobulin G1, which binds to antigen presenting cells expressing CD80 and CD86 and blocks CD28-mediated activation of T cells, potentially enhancing immune suppression (PMID: 31189043, PMID: 32052309). |
DrugClasses | |
CAS Registry Number | 332348-12-6 |
NCIT ID | C28898 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BMS-188667 | BMS-188667 | 0 | 0 |
BMS-188667 + Dexamethasone + Ixazomib | BMS-188667 Dexamethasone Ixazomib | 0 | 1 |