Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name BMS-188667
Trade Name
Synonyms Abatacept|BMS 188667|BMS188667|RG2077|RG1046|CTLA4-IGG4M|Orencia
Drug Descriptions

Abatacept (BMS-188667) is a recombinant protein containing the extracellular domain of CTLA-4 fused to immunoglobulin G1, which binds to antigen presenting cells expressing CD80 and CD86 and blocks CD28-mediated activation of T cells, potentially enhancing immune suppression (PMID: 31189043, PMID: 32052309).

DrugClasses
CAS Registry Number 332348-12-6
NCIT ID C28898

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
BMS-188667 BMS-188667 0 0
BMS-188667 + Dexamethasone + Ixazomib BMS-188667 Dexamethasone Ixazomib 0 1


Additional content available in CKB BOOST