CTX120
Drug Detail
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| Drug Name | CTX120 |
| Trade Name | |
| Synonyms | CTX-120|CTX 120 |
| Drug Descriptions |
CTX120 consists of allogeneic T-lymphocytes engineered with CRISPR/Cas9 to insert a BCMA-targeting chimeric antigen receptor (CAR) in the T-cell receptor alpha constant (TRAC) locus, and to simultaneously remove the endogenous T cell receptor (TCR) and MHC class I, which potentially results in increased cytotoxicity against BCMA-expressing tumor cells, and inhibits tumor growth (Blood (2018) 132 (Supplement 1): 1921). |
| DrugClasses | TNFRSF17 Immune Cell Therapy 27 |
| CAS Registry Number | NA |
| NCIT ID | C172741 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CTX120 | CTX120 | 0 | 1 |
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