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Drug Name | NGM120 |
Trade Name | |
Synonyms | NGM-120|NGM 120|GFRAL Antagonistic Monoclonal Antibody NGM120 |
Drug Descriptions |
NGM120 is a monoclonal antibody that targets glial-cell-derived neurotrophic factor (GDNF) family receptor alpha-like (GFRAL), which inhibits binding of its ligand GDF15 and downstream signaling (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C164217 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Gemcitabine + Nab-paclitaxel + NGM120 | Gemcitabine NGM120 Nab-paclitaxel | 0 | 0 |
NGM120 | NGM120 | 0 | 1 |