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Drug Name TST001
Trade Name
Synonyms TST-001|TST 001
Drug Descriptions

TST001 is a humanized monoclonal antibody that targets Claudin 18 isoform 2 (CLDN 18.2), which potentially induces complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and antibody-dependent cellular phagocytosis against CLDN18.2 expressing tumor cells (AACR; 2020. Abstract nr: 5183/9).

DrugClasses CLDN18.2 Antibody 19
CAS Registry Number NA
NCIT ID C173726

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capecitabine + Oxaliplatin + TST001 Capecitabine Oxaliplatin TST001 0 0
TST001 TST001 0 1


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