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Drug Name | TST001 |
Trade Name | |
Synonyms | TST-001|TST 001 |
Drug Descriptions |
TST001 is a humanized monoclonal antibody that targets Claudin 18 isoform 2 (CLDN 18.2), which potentially induces complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and antibody-dependent cellular phagocytosis against CLDN18.2 expressing tumor cells (AACR; 2020. Abstract nr: 5183/9). |
DrugClasses | CLDN18.2 Antibody 19 |
CAS Registry Number | NA |
NCIT ID | C173726 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Capecitabine + Oxaliplatin + TST001 | Capecitabine Oxaliplatin TST001 | 0 | 0 |
TST001 | TST001 | 0 | 1 |