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Drug Detail
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| Drug Name | DZD1516 |
| Trade Name | |
| Synonyms | DZD-1516|DZD 1516 |
| Drug Descriptions |
DZD1516 is an ERBB2 (HER2) inhibitor that penetrates the blood brain barrier, and upon binding to ERRB2 (HER2), prevents ERBB2 (HER2)-dependent signaling, potentially leading to tumor cell death (NCI Drug Dictionary). |
| DrugClasses | HER2 Inhibitor 43 |
| CAS Registry Number | NA |
| NCIT ID | C174039 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Ado-trastuzumab emtansine + DZD1516 | Ado-trastuzumab emtansine DZD1516 | 0 | 1 |
| Capecitabine + DZD1516 | Capecitabine DZD1516 | 0 | 1 |
| Capecitabine + DZD1516 + Trastuzumab | Capecitabine DZD1516 Trastuzumab | 0 | 1 |
| DZD1516 | DZD1516 | 0 | 1 |
| DZD1516 + Trastuzumab | DZD1516 Trastuzumab | 0 | 1 |
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