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Drug Name | pNGVL4a-hCRT-E6E7L2 |
Trade Name | |
Synonyms | pNGVL4a hCRT E6E7L2|pNGVL4a-CRT-E6E7L2|pNGVL4aCRTE6E7L2|pNGVL4a CRT E6E7L2 |
Drug Descriptions |
pNGVL4a-hCRT-E6E7L2 is a DNA vaccine that encodes calreticulin linked to the HPV-16 E6, E7, and L2 epitopes, which potentially induces CD8-positive T-cell specific immune response against tumors expressing E6 and E7, and reduces the growth of HPV-related tumors (PMID: 24594273). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
pNGVL4a-hCRT-E6E7L2 | pNGVL4a-hCRT-E6E7L2 | 0 | 0 |
pNGVL4a-hCRT-E6E7L2 + TA-CIN | TA-CIN pNGVL4a-hCRT-E6E7L2 | 0 | 0 |