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Drug Name | BLU-945 |
Trade Name | |
Synonyms | BLU 945|BLU945 |
Drug Descriptions |
BLU-945 is a wild-type-sparing 4th generation EGFR inhibitor with activity against EGFR T790M and EGFR C797S, which may block EGFR signaling and lead to tumor growth inhibition (PMID: 35838760). |
DrugClasses | EGFR Inhibitor 4th gen 16 |
CAS Registry Number | 2660250-10-0 |
NCIT ID | C180668 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BLU-945 | BLU-945 | 0 | 1 |
BLU-945 + Osimertinib | BLU-945 Osimertinib | 0 | 1 |
BLU-945 + Panitumumab | BLU-945 Panitumumab | 0 | 0 |