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Drug Name | ATA2271 |
Trade Name | |
Synonyms | M28z1XXPD1DNR CAR T cells |
Drug Descriptions |
ATA2271 (M28z1XXPD1DNR CAR T cells) consists of mesothelin-targeting chimeric antigen receptor (CAR) T cells with an ITAM motif-mutated CD3z signaling domain and a PD-1 dominant negative receptor (PD1DNR), which may enhance anti-tumor immune response (Cancer Res 2020;80(16 Suppl):Abstract nr LB-378). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ATA2271 | ATA2271 | 0 | 2 |