ASTX295
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| Drug Name | ASTX295 |
| Trade Name | |
| Synonyms | ASTX 295|ASTX-295 |
| Drug Descriptions |
ASTX295 is an inhibitor of murine double minute 2 (MDM2; HDM2) that binds to Mdm2 and inhibits proteasomal degradation of Tp53 by Mdm2, thereby restoring wild-type Tp53 and potentially leading to induction of apoptosis in tumor cells (NCI Drug Dictionary). |
| DrugClasses | MDM2 Inhibitor 23 |
| CAS Registry Number | NA |
| NCIT ID | C162749 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ASTX295 | ASTX295 | 0 | 1 |
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