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Drug Name AZD0364
Trade Name
Synonyms ATG-017|ATG017|ATG 017|AZD-0364|AZD 0364|Tizaterkib
Drug Descriptions

AZD0364 (ATG-017) is a selective ATP-competitive inhibitor of ERK1 and ERK2, which may promote apoptosis and tumor regression (PMID: 31710489, PMID: 33273059).

DrugClasses ERK Inhibitor (pan) 21 ERK1 Inhibitor 2 ERK2 Inhibitor 2
CAS Registry Number 2097416-76-5
NCIT ID C176765

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ATG-012 + AZD0364 ATG-012 AZD0364 0 0
AZD0364 AZD0364 2 0
AZD0364 + Selumetinib AZD0364 Selumetinib 0 0
AZD0364 + Trametinib AZD0364 Trametinib 0 0


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