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Drug Name | AZD0364 |
Trade Name | |
Synonyms | ATG-017|ATG017|ATG 017|AZD-0364|AZD 0364|Tizaterkib |
Drug Descriptions |
AZD0364 (ATG-017) is a selective ATP-competitive inhibitor of ERK1 and ERK2, which may promote apoptosis and tumor regression (PMID: 31710489, PMID: 33273059). |
DrugClasses | ERK Inhibitor (pan) 21 ERK1 Inhibitor 2 ERK2 Inhibitor 2 |
CAS Registry Number | 2097416-76-5 |
NCIT ID | C176765 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ATG-012 + AZD0364 | ATG-012 AZD0364 | 0 | 0 |
AZD0364 | AZD0364 | 2 | 0 |
AZD0364 + Selumetinib | AZD0364 Selumetinib | 0 | 0 |
AZD0364 + Trametinib | AZD0364 Trametinib | 0 | 0 |