Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | Tambiciclib |
| Trade Name | |
| Synonyms | GFH-009|GFH 009|GFH009|SLS009|SLS-009|SLS 009 |
| Drug Descriptions |
Tambiciclib inhibits CDK9, resulting in decreased activation of RNA Pol II and transcription of anti-apoptotic proteins, potentially leading to decreased tumor growth (J Clin Oncol 43, 2025 (suppl 16; abstr 3121, NCI Thesaurus). |
| DrugClasses | CDK9 Inhibitor 21 |
| CAS Registry Number | 2247481-08-7 |
| NCIT ID | C176965 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Azacitidine + Tambiciclib + Venetoclax | Azacitidine Tambiciclib Venetoclax | 0 | 1 |
| Tambiciclib | Tambiciclib | 0 | 1 |