CD19-CAR(Mem) T-cells
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| Drug Name | CD19-CAR(Mem) T-cells |
| Trade Name | |
| Synonyms | CD19-CAR.CD45RA-negative T-cells |
| Drug Descriptions |
CD19-CAR(Mem) T-cells are a preparation of CD45RA-negative T cells engineered to express a chimeric antigen receptor (CAR) targeting CD19, containing 4-1BB and CD3-zeta signaling domains and a variable fragment of a CD19 antibody, which may potentially lead to tumor cell lysis (PMID: 24888271). |
| DrugClasses | CD19 Immune Cell Therapy 72 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CD19-CAR(Mem) T-cells | CD19-CAR(Mem) T-cells | 0 | 0 |
| CD19-CAR(Mem) T-cells + Cyclophosphamide + Fludarabine + Mesna | CD19-CAR(Mem) T-cells Cyclophosphamide Fludarabine Mesna | 0 | 1 |
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