RM-018
Drug Detail
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| Drug Name | RM-018 |
| Trade Name | |
| Synonyms | RM018|RM 018 |
| Drug Descriptions |
RM-018 covalently binds and inhibits GTP-bound KRAS G12C by forming a complex with the chaperone protein cyclophilin A, resulting in decreased downstream signaling and potentially inhibiting tumor growth (PMID: 33824136). |
| DrugClasses | KRAS G12C inhibitor 36 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| RM-018 | RM-018 | 3 | 0 |
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