PCLX-001
Drug Detail
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| Drug Name | PCLX-001 |
| Trade Name | |
| Synonyms | PCLX 001|PCLX001|Zelenirstat |
| Drug Descriptions |
PCLX-001 inhibits the N-myristoyl-transferases NMT1 and NMT2, potentially resulting in inhibition of early B-cell receptor signaling and degradation of pERK, c-Myc, NFkappaB and CREB, which may lead to tumor cell apoptosis, decreased cell proliferation, and inhibition of tumor growth (PMID: 33093447). |
| DrugClasses | |
| CAS Registry Number | 1215011-08-7 |
| NCIT ID | C180576 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| PCLX-001 | PCLX-001 | 0 | 2 |
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