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Drug Name | SQZ-AAC-HPV |
Trade Name | |
Synonyms | Engineered AAC Loaded with HPV16 Epitopes |
Drug Descriptions |
SQZ-AAC-HPV is a cell therapy comprised of autologous red blood cells engineered to express tumor-specific antigens (TAA) and human papillomavirus (HPV) type 16 epitopes and carrying a Toll-like receptor (TLR) agonist as an adjuvant, with potential to induce an anti-tumor immune response against HPV16- or TAA-expressing tumor cells (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C184978 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Ipilimumab + Nivolumab + SQZ-AAC-HPV | Ipilimumab Nivolumab SQZ-AAC-HPV | 0 | 1 |
Ipilimumab + SQZ-AAC-HPV | Ipilimumab SQZ-AAC-HPV | 0 | 1 |
SQZ-AAC-HPV | SQZ-AAC-HPV | 0 | 1 |