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Drug Name | H3K27M peptide vaccine |
Trade Name | |
Synonyms | H3K27M long peptide vaccine |
Drug Descriptions |
H3K27M peptide vaccine is comprised of a 27mer immunogenic peptide derived from histone H3 harboring the K27M mutation (also referred to as K28M), which may lead to activation of immune response against tumor cells expressing H3K27M and tumor growth inhibition (PMID: 28811969). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C180377 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + H3K27M peptide vaccine + Imiquimod | Atezolizumab H3K27M peptide vaccine Imiquimod | 0 | 1 |
H3K27M peptide vaccine | H3K27M peptide vaccine | 0 | 0 |