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| Drug Name | AK127 |
| Trade Name | |
| Synonyms | AK-127|AK 127 |
| Drug Descriptions |
AK127 is a monoclonal antibody that targets and binds to the T-cell immunoreceptor with Ig and ITIM domains (TIGIT), thereby inhibiting binding with ligands CD112 and CD155, and potentially resulting in an enhanced immune response against tumor cells (NCI Drug Dictionary). |
| DrugClasses | TIGIT Antibody 20 |
| CAS Registry Number | NA |
| NCIT ID | C184307 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AK127 | AK127 | 0 | 0 |
| AK127 + Cadonilimab | AK127 Cadonilimab | 0 | 1 |