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Drug Name | ATG-101 |
Trade Name | |
Synonyms | ATG101|ATG 101|xirestomig |
Drug Descriptions |
ATG-101 is a tetravalent bispecific antibody targeting PD-L1 (CD274) and TNFRSF9 (4-1BB), which activates TNFRSF9 (4-1BB) signaling and blocks PD-1/PD-L1 interaction, potentially leading to an enhanced antitumor immune response and inhibition of tumor growth (PMID: 38501978). |
DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 TNFRSF9 Antibody 32 |
CAS Registry Number | 2756879-35-1 |
NCIT ID | C190124 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ATG-101 | ATG-101 | 0 | 1 |