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| Drug Name | HLX301 |
| Trade Name | |
| Synonyms | HLX 301|HLX-301 |
| Drug Descriptions |
HLX301 is a bispecific antibody that targets T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT) and PD-L1 (CD274), thereby inhibiting the binding of TIGIT with its ligands CD112 and CD155 and the activation of the PD-L1 receptor, potentially leading to increased antitumor immune response (NCI Drug Dictionary). |
| DrugClasses | PD-L1/PD-1 antibody 121 TIGIT Antibody 19 |
| CAS Registry Number | NA |
| NCIT ID | C185160 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| HLX301 | HLX301 | 0 | 1 |
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