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Drug Name HLX301
Trade Name
Synonyms HLX 301|HLX-301
Drug Descriptions

HLX301 is a bispecific antibody that targets T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT) and PD-L1 (CD274), thereby inhibiting the binding of TIGIT with its ligands CD112 and CD155 and the activation of the PD-L1 receptor, potentially leading to increased antitumor immune response (NCI Drug Dictionary).

DrugClasses PD-L1/PD-1 antibody 121 TIGIT Antibody 19
CAS Registry Number NA
NCIT ID C185160

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Therapy Name Drugs Efficacy Evidence Clinical Trials
HLX301 HLX301 0 1


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