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| Drug Name | NK-92/5.28.z |
| Trade Name | |
| Synonyms | HER2.taNK|Anti-HER2-CAR-CD28zeta NK-92 Cells |
| Drug Descriptions |
NK-92/5.28.z are NK-92 natural killer cell line-derived cells engineered to express a chimeric antigen receptor (CAR) that targets ERBB2 (HER2) and contains CD28 and the signaling domain from CD3zeta, which potentially results in tumor cell cytotoxicity and inhibition of tumor growth (PMID: 28879551, PMID: 25373520). |
| DrugClasses | HER2 (ERBB2) Immune Cell Therapy 9 |
| CAS Registry Number | NA |
| NCIT ID | C154568 |
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