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Drug Name CPO107
Trade Name
Synonyms CPO 107|CPO-107|JMT601
Drug Descriptions

CPO107 is a bispecific fusion protein consisting ofatumumab, an anti-CD20 antibody, linked to signal regulatory protein alpha (SIRPalpha), which targets CD20 and CD47 expressed on tumor cells, potentially leading to antibody-dependent and complement-mediated tumor cell cytotoxicity and increased tumor cell phagocytosis and anti-tumor T-cell response (NCI Drug Dictionary).

DrugClasses CD20 Antibody 24 CD47 Antibody 31
CAS Registry Number NA
NCIT ID C179727

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CPO107 CPO107 0 1


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