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Drug Detail
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| Drug Name | CPO107 |
| Trade Name | |
| Synonyms | CPO 107|CPO-107|JMT601 |
| Drug Descriptions |
CPO107 is a bispecific fusion protein consisting ofatumumab, an anti-CD20 antibody, linked to signal regulatory protein alpha (SIRPalpha), which targets CD20 and CD47 expressed on tumor cells, potentially leading to antibody-dependent and complement-mediated tumor cell cytotoxicity and increased tumor cell phagocytosis and anti-tumor T-cell response (NCI Drug Dictionary). |
| DrugClasses | CD20 Antibody 25 CD47 Antibody 31 |
| CAS Registry Number | NA |
| NCIT ID | C179727 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CPO107 | CPO107 | 0 | 1 |
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