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Drug Name | TAC01-HER2 |
Trade Name | |
Synonyms | TAC 01-HER2|TAC-01-HER2|TAC-engineered T Cells TAC01-HER2 |
Drug Descriptions |
TAC01-HER2 are autologous T-lymphocytes engineered to express an ERBB2 (HER2) T-Cell Antigen-Coupler (TAC), which leads to activation and targeting of T-lymphocytes to ERBB2 (HER2)-positive tumor cells, potentially resulting in inhibition of tumor growth (Cancer Res 2022;82(12_Suppl):Abstract nr CT247). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C178298 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cyclophosphamide + Fludarabine + TAC01-HER2 | Cyclophosphamide Fludarabine TAC01-HER2 | 0 | 1 |
TAC01-HER2 | TAC01-HER2 | 0 | 0 |