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Drug Name | Anti-KRAS G12D TCR cells |
Trade Name | |
Synonyms | Anti-KRAS G12D T-cell receptor cells |
Drug Descriptions |
Anti-KRAS G12D TCR cells are autologous T-cells engineered to express HLA-C*08:02-restricted T-cell receptors (TCR) targeting KRAS G12D, potentially leading to inhibition of tumor growth (PMID: 35648703). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Aldesleukin + Anti-KRAS G12D TCR cells + GRT-C903 + GRT-R904 | Aldesleukin Anti-KRAS G12D TCR cells GRT-C903 GRT-R904 | 0 | 1 |
Anti-KRAS G12D TCR cells | Anti-KRAS G12D TCR cells | 0 | 0 |