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Drug Name AGEN1777
Trade Name
Synonyms AGEN-1777|AGEN 1777|BMS-986442|BMS986442|BMS 986442
Drug Descriptions

AGEN1777 (BMS-986442) is a bispecific antibody targeting TIGIT and CD96, which potentially induces enhanced anti-tumor immune response (Cancer Res (2024) 84 (6_Supplement): 3915).

DrugClasses TIGIT Antibody 19
CAS Registry Number NA
NCIT ID C183161

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AGEN1777 AGEN1777 0 1
AGEN1777 + Carboplatin + Nivolumab + Paclitaxel AGEN1777 Carboplatin Nivolumab Paclitaxel 0 1
AGEN1777 + Carboplatin + Nivolumab + Pemetrexed Disodium AGEN1777 Carboplatin Nivolumab Pemetrexed Disodium 0 1
AGEN1777 + Docetaxel + Nivolumab AGEN1777 Docetaxel Nivolumab 0 1
AGEN1777 + Nivolumab AGEN1777 Nivolumab 0 1
AGEN1777 + unspecified PD-1 antibody AGEN1777 unspecified PD-1 antibody 0 1


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