SAR445877
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| Drug Name | SAR445877 |
| Trade Name | |
| Synonyms | SAR 445877|SAR-445877|KD 050|KD-050|KD050|mut-1N-IL-15/38B2 |
| Drug Descriptions |
SAR445877 is an antibody cytokine fusion molecule comprising an anti-PD-1 (PDCD1) antibody linked to a mutated fusion of human IL15 and human IL15 receptor-alpha sushi domain, which potentially inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2972). |
| DrugClasses | Immune Checkpoint Inhibitor 150 PD-L1/PD-1 antibody 132 |
| CAS Registry Number | NA |
| NCIT ID | C192821 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ADG126 + SAR445877 | ADG126 SAR445877 | 0 | 1 |
| Bevacizumab + SAR445877 | Bevacizumab SAR445877 | 0 | 1 |
| Cetuximab + SAR445877 | Cetuximab SAR445877 | 0 | 1 |
| SAR445877 | SAR445877 | 0 | 2 |
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