XTX301
Drug Detail
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| Drug Name | XTX301 |
| Trade Name | |
| Synonyms | XTX 301|XTX-301 |
| Drug Descriptions |
XTX301 comprises IL-12 linked to an IL12RB2-derived masking domain via a protease-sensitive linker that is cleaved by proteases in the tumor microenvironment, which activates IL-12 signaling and potentially inhibits tumor growth (PMID: 38030380). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C199629 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| XTX301 | XTX301 | 0 | 1 |
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