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Drug Name | XTX301 |
Trade Name | |
Synonyms | XTX 301|XTX-301 |
Drug Descriptions |
XTX301 comprises IL-12 linked to an IL12RB2-derived masking domain via a protease-sensitive linker that is cleaved by proteases in the tumor microenvironment, which activates IL-12 signaling and potentially inhibits tumor growth (PMID: 38030380). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C199629 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
XTX301 | XTX301 | 0 | 1 |