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Drug Name | CTX131 |
Trade Name | |
Synonyms | CTX-131|CTX 131 |
Drug Descriptions |
CTX131 are allogeneic T-lymphocytes engineered to harbor modifications of Regnase-1 and TGFBR2 and express a chimeric antigen receptor (CAR) targeting CD70, which potentially lead to enhanced antitumor immune response and inhibition of tumor growth (Cancer Res (2023) 83 (7_Supplement): ND02). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C200041 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CTX131 | CTX131 | 0 | 2 |