INX-315
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| Drug Name | INX-315 |
| Trade Name | |
| Synonyms | INX315|INX 315 |
| Drug Descriptions |
INX-315 inhibits CDK2, potentially leading to decreased Rb phosphorylation, cell cycle arrest, and reduced tumor cell proliferation and growth in CCNE1-amplified tumors (PMID: 38047585). |
| DrugClasses | CDK2 Inhibitor 31 |
| CAS Registry Number | NA |
| NCIT ID | C200051 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abemaciclib + Fulvestrant + INX-315 | Abemaciclib Fulvestrant INX-315 | 0 | 1 |
| Abemaciclib + INX-315 | Abemaciclib INX-315 | 0 | 0 |
| Fulvestrant + INX-315 | Fulvestrant INX-315 | 0 | 1 |
| INX-315 | INX-315 | 0 | 1 |
CKB BOOST