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Drug Name | INX-315 |
Trade Name | |
Synonyms | INX315|INX 315 |
Drug Descriptions |
INX-315 inhibits CDK2, potentially leading to decreased Rb phosphorylation, cell cycle arrest, and reduced tumor cell proliferation and growth in CCNE1-amplified tumors (PMID: 38047585). |
DrugClasses | CDK2 Inhibitor 31 |
CAS Registry Number | NA |
NCIT ID | C200051 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abemaciclib + INX-315 | Abemaciclib INX-315 | 0 | 0 |
INX-315 | INX-315 | 0 | 1 |