HCW9218
Drug Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | HCW9218 |
| Trade Name | |
| Synonyms | HCW-9218|HCW 9218 |
| Drug Descriptions |
HCW9218 is a fusion protein complex composed of TGFBR2 extracellular domains, a variant of IL15, and IL15RA sushi domains, which binds to and sequesters TGFB1, reducing downstream signaling and potentially increases antitumor immune response and tumor cell death (PMID: 34091051, PMID: 35051615). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C186737 |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Docetaxel + HCW9218 | Docetaxel HCW9218 | 0 | 0 |
| Gemcitabine + HCW9218 + Nab-paclitaxel | Gemcitabine HCW9218 Nab-paclitaxel | 0 | 0 |
| HCW9218 | HCW9218 | 0 | 2 |
CKB BOOST