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| Drug Name | CB-011 |
| Trade Name | |
| Synonyms | CB 011|CB011 |
| Drug Descriptions |
CB-011 are allogeneic T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting BCMA (TNFRSF17), which also has disruption of TRAC, deletion of B2M, and insertion of a B2M-HLA-E fusion protein transgene to reduce rejection, potentially leading to enhanced CAR-T cell persistence and antitumor activity (Cancer Res (2022) 82 (12_Supplement): LB009). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C199479 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CB-011 | CB-011 | 0 | 1 |
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