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Drug Name | SIRPant-M |
Trade Name | |
Synonyms | SI-101|SIRPantM|SI101|SI 101 |
Drug Descriptions |
SIRPant-M are autologous macrophages activated ex vivo and engineered to have depletion of SIRPa, which potentially induce a cytotoxic T-lymphocyte (CTL) response against tumor cells (Blood (2023) 142 (Supplement 1): 4856, NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C208268 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
SIRPant-M | SIRPant-M | 0 | 1 |