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Drug Name | RO7589831 |
Trade Name | |
Synonyms | RO-7589831|RO 7589831|VVD-133214|RG 6457|RG-6457|VVD-214 |
Drug Descriptions |
RO7589831 covalently binds to and inhibits WRN, resulting in decreased ATPase and helicase and activity, which potentially induces DNA damage and cell cycle arrest and leads to inhibition of tumor growth (PMID: 38658751). |
DrugClasses | |
CAS Registry Number | 3026500-20-6 |
NCIT ID | C204483 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
RO7589831 | RO7589831 | 0 | 1 |