NY-ESO-1 TCR/IL-15 NK cells
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| Drug Name | NY-ESO-1 TCR/IL-15 NK cells |
| Trade Name | |
| Synonyms | Allogeneic anti-NY-ESO-1 TCR-transduced IL-15-expressing CB-derived NK cells |
| Drug Descriptions |
NY-ESO-1 TCR/IL-15 NK cells are allogeneic natural killer (NK) cells derived from cord blood that are engineered to express a T-cell receptor (TCR) targeting NY-ESO-1 and to express IL-15, which potentially induce toxicity in tumor cells expressing NY-ESO-1 (NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C201721 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cyclophosphamide + Fludarabine + NY-ESO-1 TCR/IL-15 NK cells | Cyclophosphamide Fludarabine NY-ESO-1 TCR/IL-15 NK cells | 0 | 2 |
| NY-ESO-1 TCR/IL-15 NK cells | NY-ESO-1 TCR/IL-15 NK cells | 0 | 0 |
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