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Drug Name | CD371-YSNVZIL-18 CAR T cells |
Trade Name | |
Synonyms | CD371-specific/YSNVz/IL-18 CAR T-cells |
Drug Descriptions |
CD371-YSNVZIL-18 CAR T cells are T-lymphocytes engineered to express IL-18 and a chimeric antigen receptor (CAR) that targets CLEC12A (CD371), which potentially induce increased antitumor immune response and cytotoxicity against CLEC12A (CD371)-expressing tumor cells (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C201527 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CD371-YSNVZIL-18 CAR T cells | CD371-YSNVZIL-18 CAR T cells | 0 | 1 |