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| Drug Name | L1CAM-specific CAR+EGFRt+ T cells |
| Trade Name | |
| Synonyms | CD171-specific CAR-EGFRt-expressing T lymphocytes |
| Drug Descriptions |
L1CAM-specific CAR+EGFRt+ T cells are autologous T-cells engineered to express a chimeric antigen receptor (CAR) targeting L1CAM (CD171) and truncated EGFR (EGFRt), which may increase cytotoxicity against L1CAM-expressing tumor cells (NCI Thesaurus). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C201687 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| L1CAM-specific CAR+EGFRt+ T cells | L1CAM-specific CAR+EGFRt+ T cells | 0 | 1 |
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