Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | LY4101174 |
| Trade Name | |
| Synonyms | LY 4101174|LY-4101174|ETx22|ETx-22|ETx 22 |
| Drug Descriptions |
LY4101174 is an antibody-drug conjugate (ADC) comprising a Nectin4 antibody conjugated to the topoisomerase I inhibitor exatecan, which induces double-stranded DNA breaks and potentially inhibits tumor growth (PMID: 39440991). |
| DrugClasses | NECTIN4 Antibody 11 |
| CAS Registry Number | NA |
| NCIT ID | C204904 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| LY4101174 | LY4101174 | 0 | 1 |