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Drug Name | oHSV2-PD-L1/CD3-BsAb |
Trade Name | |
Synonyms | |
Drug Descriptions |
oHSV2-PD-L1/CD3-BsAb is an oncolytic virus derived from herpes simplex virus type 2 and engineered to express a bispecific antibody targeting both CD274 (PD-L1) and CD3, which may increase T-cell activation and decrease tumor growth (PMID: 35272497). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
oHSV2-PD-L1/CD3-BsAb | oHSV2-PD-L1/CD3-BsAb | 0 | 1 |