EGFRt/19-28z/IL-12 CAR-T cells
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| Drug Name | EGFRt/19-28z/IL-12 CAR-T cells |
| Trade Name | |
| Synonyms | EGFRt/19-28z/IL-12 CAR T cells |
| Drug Descriptions |
EGFRt/19-28z/IL-12 CAR-T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD19 linked to CD3zeta and CD28 signaling domains, truncated EGFR, and the cytokine IL-12, which potentially induce cytotoxicity against CD19-expressing tumor cells (NCI Drug Dictionary). |
| DrugClasses | CD19 Immune Cell Therapy 72 |
| CAS Registry Number | NA |
| NCIT ID | C204501 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| EGFRt/19-28z/IL-12 CAR-T cells | EGFRt/19-28z/IL-12 CAR-T cells | 0 | 1 |
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