Drug Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | AJ1-11095 |
| Trade Name | |
| Synonyms | AJ1 11095 |
| Drug Descriptions |
AJ1-11095 is a non-covalent JAK2 inhibitor that binds active and inactive JAK2 and prevents heterodimerization with JAK1 and TYK2, which may induce apoptosis and inhibit proliferation in tumor cells (Blood (2024) 144 (Supplement 1): 3147.1, NCI Drug Dictionary). |
| DrugClasses | JAK2 Inhibitor 19 |
| CAS Registry Number | NA |
| NCIT ID | C210745 |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| AJ1-11095 | AJ1-11095 | 0 | 1 |
CKB BOOST