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| Drug Name | BHV-1510 |
| Trade Name | |
| Synonyms | PBI 410|PBI410|GQ1010|GQ-1010|GQ 1010|PBI-410|BHV1510|BHV 1510 |
| Drug Descriptions |
BHV-1510 (PBI-410) is an antibody-drug conjugate (ADC) comprising an antibody targeting TROP2 linked to a camptothecin analogue, which potentially induces cytotoxicity against TROP2-expressing tumor cells and antitumor activity (Cancer Res (2024) 84 (6_Supplement): 7168; Cancer Res (2023) 83 (7_Supplement): 1549). |
| DrugClasses | TROP2 Antibody 18 |
| CAS Registry Number | NA |
| NCIT ID | C207910 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| BHV-1510 | BHV-1510 | 0 | 1 |
| BHV-1510 + Cemiplimab | BHV-1510 Cemiplimab | 0 | 1 |