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Drug Name | AdAPT-001 |
Trade Name | |
Synonyms | AdAPT 001|AdAPT001 |
Drug Descriptions |
AdAPT-001 is an oncolytic adenovirus engineered to express a fusion protein composed of soluble TGFBR2 and the Fc region of IgG1, which binds to and sequesters TGFbeta, potentially inhibiting downstream signaling and tumor growth (PMID: 35950603). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C179574 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AdAPT-001 | AdAPT-001 | 0 | 1 |
AdAPT-001 + unspecified immune checkpoint inhibitor | AdAPT-001 unspecified immune checkpoint inhibitor | 0 | 1 |