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Drug Name | SCRI-CARB7H3 |
Trade Name | |
Synonyms | 4-1BBzeta-B7H3-EGFRt-DHFR |
Drug Descriptions |
SCRI-CARB7H3 comprises CD4- and CD8-positive autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD276 (B7-H3) and truncated EGFR (EGFRt), which potentially induce an enhanced antitumor immune response (PMID: 36259971). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
SCRI-CARB7H3 | SCRI-CARB7H3 | 0 | 1 |