SCRI-CARB7H3
Drug Detail
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| Drug Name | SCRI-CARB7H3 |
| Trade Name | |
| Synonyms | 4-1BBzeta-B7H3-EGFRt-DHFR |
| Drug Descriptions |
SCRI-CARB7H3 comprises CD4- and CD8-positive autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD276 (B7-H3) and truncated EGFR (EGFRt), which potentially induce an enhanced antitumor immune response (PMID: 36259971). |
| DrugClasses | CD276 Immune Cell Therapy 10 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| SCRI-CARB7H3 | SCRI-CARB7H3 | 0 | 1 |
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