GEN1286
Drug Detail
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| Drug Name | GEN1286 |
| Trade Name | |
| Synonyms | PRO1286 |
| Drug Descriptions |
GEN1286 is an antibody-drug conjugate (ADC) comprising a bispecific antibody that targets EGFR and cMET linked to the topoisomerase I inhibitor sesutecan, which may induce cytotoxicity against tumor cells expressing EGFR and/or MET and inhibit tumor growth (Cancer Res (2024) 84 (6_Supplement): 6580). |
| DrugClasses | EGFR Antibody 73 MET Antibody 38 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| GEN1286 | GEN1286 | 0 | 1 |
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