TNG456
Drug Detail
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| Drug Name | TNG456 |
| Trade Name | |
| Synonyms | TNG-456|TNG 456 |
| Drug Descriptions |
TNG456 selectively inhibits PRMT5 in MTAP-null cells, which potentially leads to decreased tumor cell growth (Cancer Res (2025) 85 (8_Supplement_1): 462). |
| DrugClasses | PRMT5 Inhibitor 21 |
| CAS Registry Number | NA |
| NCIT ID | C215699 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abemaciclib + TNG456 | Abemaciclib TNG456 | 0 | 1 |
| TNG456 | TNG456 | 0 | 1 |
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