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| Drug Name | CLBR001 |
| Trade Name | |
| Synonyms | CLBR-001|CLBR 001|Autologous alpha-PNE CAR T-cells CLBR001 |
| Drug Descriptions |
CLBR001 is a switchable CAR-T therapy that comprises autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets a unique peptide epitope on a tumor antigen-specific switch molecule, which potentially results in activation of CAR-T cells and tumor cell killing in the presence of the switch molecule (Blood (2021) 138 (Supplement 1): 1695, NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C175578 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ABBV-461 + CLBR001 | ABBV-461 CLBR001 | 0 | 1 |
| CLBR001 | CLBR001 | 0 | 0 |