Autologous anti-CCR9 CAR-T cells
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| Drug Name | Autologous anti-CCR9 CAR-T cells |
| Trade Name | |
| Synonyms | CARCCR9 T cells|CCR9 CAR T cells |
| Drug Descriptions |
Autologous anti-CCR9 CAR-T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CCR9 linked to CD8 transmembrane domain and 4-1BB-CD3zeta endodomain, which potentially induce cytotoxicity against CCR9-expressing tumor cells and are resistant to fratricide (PMID: 35507686). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Autologous anti-CCR9 CAR-T cells | Autologous anti-CCR9 CAR-T cells | 0 | 1 |
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