1XX BCMA CAR-T cells
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| Drug Name | 1XX BCMA CAR-T cells |
| Trade Name | |
| Synonyms | Anti-BCMA 1XX-enhanced CAR T-cells|1XX-BCMA CAR T-cells |
| Drug Descriptions |
1XX BCMA CAR-T cells are CRISPR-modified T-cells engineered to express a chimeric antigen receptor (CAR) targeting TNFRSF17 (BCMA) with a CD28 costimulatory domain and a 1XX-modified CD3zeta signaling domain, which potentially inhibit tumor growth (Blood (2025) 146 (Supplement 1): 5958). |
| DrugClasses | TNFRSF17 Immune Cell Therapy 28 |
| CAS Registry Number | NA |
| NCIT ID | C223225 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| 1XX BCMA CAR-T cells | 1XX BCMA CAR-T cells | 0 | 1 |
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