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| Drug Name | GB-5267 |
| Trade Name | |
| Synonyms | GB5267|GB 5267 |
| Drug Descriptions |
GB-5267 are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting MUC16 linked to a co-stimulatory 4-1BB domain and TCR/CD3zeta and expressing IL18, which potentially induces antitumor immune response (NCI Thesaurus). |
| DrugClasses | MUC16 Targeted Therapy 12 |
| CAS Registry Number | NA |
| NCIT ID | C226454 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| GB-5267 | GB-5267 | 0 | 1 |